SCHEMBL23405652

SCHEMBL23405652

CCCCCCc1cccc2c(CCCCCC)c(N)ccc12

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 9/20 0.46
LIPG Q9Y5X9 1/20 0.42
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
PARP1 P09874 1/20 0.40
SRC P12931 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5748397 0.83 TLR8 (0.50) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL5745315 0.83 TLR8 (0.50) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL5745523 0.83 TLR8 (0.50) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL23405536 0.83 ALDH1A1 (0.38) TLR8PARP1
SCHEMBL30217449 0.83 TLR8 (0.50) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL2293519 0.82 LIPG (0.49) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL365190 0.82 LIPG (0.49) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL4308876 0.82 LIPG (0.49) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL9019468 0.82 LIPG (0.49) TLR8LIPGBIDMCL1BCL2L1
SCHEMBL119639 0.82 LIPG (0.49) TLR8LIPGBIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11151345-B2 Polarization-based coding/encryption using organic charge-transfer materials NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2021-10-19 US claimed
US-20210165984-A1 Polarization-based coding/encryption using organic charge-transfer materials NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2021-06-03 US claimed
US-11151345-B2 Polarization-based coding/encryption using organic charge-transfer materials NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2021-10-19 US disclosed
US-20210165984-A1 Polarization-based coding/encryption using organic charge-transfer materials NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2021-06-03 US disclosed