Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544670 | 0.80 | ALDH1A1 (0.41) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL1092188 | 0.75 | NPC1 (0.50) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL28644537 | 0.75 | ALDH1A1 (0.48) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL28174508 | 0.74 | S1PR1 (0.51) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL29911234 | 0.73 | NPC1 (0.49) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL23432313 | 0.73 | NPC1 (0.49) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL28595835 | 0.73 | S1PR1 (0.46) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL28349136 | 0.72 | NPC1 (0.44) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL22231981 | 0.71 | POLB (0.44) | NPC1RAB9ATP53LMNASMN1; SMN2 | |
| SCHEMBL31047817 | 0.71 | NPC1 (0.50) | NPC1RAB9ATP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585145-B | Polycyclic compound and organic light emitting device including the same | 株式会社LG化学 | 2023-09-29 | — | — | CN | disclosed |
| CN-113853694-B | organic light emitting device | 株式会社LG化学 | 2023-09-05 | — | — | CN | disclosed |
| CN-110719914-B | Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2023-07-28 | — | — | CN | disclosed |
| CN-114539300-A | Light emitting device and polycyclic compound for light emitting device | 三星显示有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20210167288-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2021-06-03 | — | — | US | disclosed |
| CN-109476682-B | Compound and organic light-emitting element comprising same | 株式会社LG化学 | 2021-05-14 | — | — | CN | disclosed |
| CN-110719914-A | Polycyclic aromatic compound | 学校法人关西学院 | 2020-01-21 | — | — | CN | disclosed |
| CN-109476682-A | Compound and organic light-emitting element comprising same | 株式会社LG化学 | 2019-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210167288-A1 | POLYCYCLIC AROMATIC COMPOUND | ARNT, TYR, AHR | NPC1 2691/4885RAB9A 4272/4885TP53 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.