Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549802 | 0.83 | POLB (0.41) | POLBALDH1A1KMT2AMAPTGAA | |
| SCHEMBL28349136 | 0.79 | NPC1 (0.44) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28542216 | 0.78 | ALDH1A1 (0.37) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28465019 | 0.75 | NPC1 (0.44) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL23406367 | 0.71 | NPC1 (0.44) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL5953676 | 0.71 | TSHR (0.52) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL22232046 | 0.71 | POLB (0.40) | POLBNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28318702 | 0.70 | NPC1 (0.50) | NPC1RAB9AALDH1A1KMT2ATP53 | |
| SCHEMBL18161362 | 0.70 | KIF11 (0.47) | NPC1RAB9AALDH1A1KMT2ATP53 | |
| SCHEMBL2329256 | 0.70 | POLB (0.61) | POLBNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089523-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2022-03-24 | — | — | US | claimed |
| EP-3911629-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2021-11-24 | — | — | EP | claimed |
| CN-113454063-A | 3-substituted phenylamidine compounds, preparation method and application thereof | PI工业有限公司 | 2021-09-28 | — | — | CN | claimed |
| WO-2020148617-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-07-23 | — | — | WO | claimed |
| CN-112585145-B | Polycyclic compound and organic light emitting device including the same | 株式会社LG化学 | 2023-09-29 | — | — | CN | disclosed |
| CN-115448935-A | Polycyclic aromatic compound | 学校法人关西学院 | 2022-12-09 | — | — | CN | disclosed |
| US-20220089523-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2022-03-24 | — | — | US | disclosed |
| EP-3911629-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2021-11-24 | — | — | EP | disclosed |
| CN-113454063-A | 3-substituted phenylamidine compounds, preparation method and application thereof | PI工业有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112585145-A | Polycyclic compound and organic light emitting device including the same | 株式会社LG化学 | 2021-03-30 | — | — | CN | disclosed |
| WO-2020148617-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089523-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | H1-3, PRMT7, PFAS | POLB 2700/4885NPC1 3413/4885RAB9A 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.