Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215516 | 0.80 | KEAP1 (0.58) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL8668318 | 0.76 | ALDH1A1 (0.61) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL28200575 | 0.76 | KEAP1 (0.54) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL12195215 | 0.76 | KEAP1 (0.54) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL1602027 | 0.76 | KEAP1 (0.54) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL5864 | 0.76 | KEAP1 (0.67) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL28435620 | 0.76 | KEAP1 (0.54) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL28268456 | 0.75 | CES1 (0.50) | TDP1ALDH1A1HDAC8HDAC6MAPK1 | |
| SCHEMBL2240494 | 0.74 | KEAP1 (0.64) | KEAP1TDP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL28338568 | 0.74 | KEAP1 (0.64) | KEAP1TDP1ALDH1A1FFAR1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163408-A1 | METHOD FOR PREPARING A POLYFLUORINATED COMPOUND | ETH ZURICH (CH) | 2021-06-03 | — | — | US | disclosed |
| CN-112689623-A | Process for preparing polyfluoro compounds | 瑞士苏黎世联邦理工学院 | 2021-04-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163408-A1 | METHOD FOR PREPARING A POLYFLUORINATED COMPOUND | AFF4, AR, AFF2 | KEAP1 2779/4885TDP1 3779/4885ALDH1A1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.