SCHEMBL5864

SCHEMBL5864

O=C(Cl)CCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.67
FFAR1 O14842 2/20 0.61
ALDH1A1 P00352 2/20 0.61
HDAC2 Q92769 3/20 0.57
HDAC8 Q9BY41 3/20 0.57
HDAC6 Q9UBN7 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
HDAC1 Q13547 5/20 0.56
HDAC3 O15379 2/20 0.56
HDAC4 P56524 2/20 0.56
HDAC7 Q8WUI4 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC9 Q9UKV0 2/20 0.56
HDAC5 Q9UQL6 2/20 0.56
MAPK1 P28482 1/20 0.56
ADRA1A P35348 1/20 0.56
SLC6A3 Q01959 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPT P10636 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28338568 0.98 KEAP1 (0.64) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL2240494 0.98 KEAP1 (0.64) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL8591123 0.90 KEAP1 (0.55) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL9135914 0.87 FFAR1 (0.50) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL1912568 0.87 FFAR1 (0.71) KEAP1FFAR1HDAC2HDAC1HTT
Tetrahydrofuran SCHEMBL28927730 0.87 FKBP1A (0.57) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL61491 0.86 HDAC1 (0.69) KEAP1FFAR1ALDH1A1HDAC2HDAC8
Trifluoroacetamide SCHEMBL28335370 0.85 CES1 (0.50) KEAP1FFAR1ALDH1A1HDAC2HDAC8
SCHEMBL384438 0.85 MAPT (0.68) KEAP1HDAC2HDAC8HDAC6TDP1
SCHEMBL27538484 0.85 HDAC1 (0.67) KEAP1FFAR1ALDH1A1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4259 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US claimed
CN-120058652-A Tuber-shogaol A derivative and preparation method and application thereof 湖南医药学院 2025-05-30 CN claimed
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
CN-119462646-A Substituted tetrahydro-beta-carboline derivative, synthesis method and application thereof 江苏科技大学 2025-02-18 CN claimed
CN-116180273-B Photosensitive silk thread and preparation method thereof 东莞市博斯蒂新材料有限公司 2025-02-14 CN claimed
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-119098067-A Method for producing reverse osmosis membrane and reverse osmosis membrane produced thereby 沃顿科技股份有限公司 2024-12-10 CN claimed
CN-118955940-A Agricultural and forestry waste-based thermoplastic plastic and preparation method thereof 西南林业大学 2024-11-15 CN claimed
CN-118772121-A Golgi body targeting near-infrared fluorescent probe for detecting chymotrypsin, preparation method and application thereof 许昌学院 2024-10-15 CN claimed
WO-2000061536-A2 SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS GLOBOASIA, L.L.C. (US) 2000-10-19 WO claimed
EP-1005443-A1 2000-06-07 EP claimed
US-5939581-A Processes for preparing hydrocinnamic acid FIRST CHEMICAL CORPORATION (US) 1999-08-17 US claimed
WO-1999008989-A1 PROCESSES FOR PREPARING HYDROCINNAMIC ACID FIRST CHEMICAL CORPORATION (US) 1999-02-25 WO claimed
US-5744071-A Processes for preparing alkynyl ketones and precursors thereof FMC CORPORATION (US) 1998-04-28 US claimed
WO-1996033199-A1 PROCESS FOR MAKING 1-HYDROXYBISPHOSPHONATES MERCK & CO., INC. (US) 1996-10-24 WO claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
US-4481368-A Process for preparing α-keto-carboxylic acids from acyl halides ETHYL CORPORATION (US) 1984-11-06 US claimed
US-4481369-A VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE ETHYL CORPORATION (US) 1984-11-06 US claimed
US-4272502-A Process for preparing gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1981-06-09 US claimed