Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.85 |
| ▸ | RAB9A | P51151 | 12/20 | 0.85 |
| ▸ | NPC1 | O15118 | 10/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 10/20 | 0.60 |
| ▸ | GLA | P06280 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 10/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620797 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23407685 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23407556 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23407619 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6390060 | 0.78 | RAB9A (1.00) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23407590 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17626720 | 0.76 | NPC1 (0.58) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1494834 | 0.74 | KDM4E (0.83) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5305847 | 0.74 | ALDH1A1 (0.76) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5308526 | 0.74 | RAB9A (0.90) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704105-B9 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2025-03-05 | — | — | EP | disclosed |
| EP-3704105-B1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD (GB) | 2024-10-16 | — | — | EP | disclosed |
| US-20220372027-A1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD. (GB) | 2022-11-24 | — | — | US | disclosed |
| US-11345694-B2 | Antibacterial compounds | DISCUVA LTD. (GB) | 2022-05-31 | — | — | US | disclosed |
| US-11345694-B2 | Antibacterial compounds | DISCUVA LTD. (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20210163460-A1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD. (GB) | 2021-06-03 | — | — | US | disclosed |
| US-20210163460-A1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD. (GB) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345694-B2 | Antibacterial compounds | CFTR, MRPL21, NQO1 | ALDH1A1 1908/4885KDM4E 4533/4885RAB9A 802/4885 |
| US-20220372027-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, NRDC, PGLS | ALDH1A1 3982/4885KDM4E 3363/4885RAB9A 512/4885 |
| US-20210163460-A1 | ANTIBACTERIAL COMPOUNDS | CFTR, MRPL21, NQO1 | ALDH1A1 1908/4885KDM4E 4533/4885RAB9A 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.