Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23407743 | 0.81 | TTR (0.57) | TTRSLC6A2SLC6A3MAPTTDP1 | |
| SCHEMBL23391597 | 0.80 | TTR (0.48) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23391525 | 0.80 | TTR (0.48) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23391626 | 0.79 | TTR (0.46) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23391581 | 0.74 | SMN1; SMN2 (0.47) | TTRMAPTTDP1ALDH1A1 | |
| SCHEMBL676629 | 0.73 | TTR (0.73) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL29636402 | 0.72 | TRPV4 (0.55) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL2127233 | 0.72 | TRPV4 (0.55) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23391578 | 0.71 | TTR (0.40) | TTRSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23407744 | 0.71 | TTR (0.40) | TTRSLC6A4SLC6A2SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MANBA, MGAM, GUSB | TTR 4399/4885SLC6A4 4430/4885SLC6A2 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.