Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 3/20 | 0.47 |
| ▸ | BTK | Q06187 | 4/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729063 | 1.00 | TTBK1 (0.47) | TTBK1TTBK2BTKJAK3PTK2 | |
| SCHEMBL23409026 | 0.81 | BTK (0.50) | TTBK1TTBK2BTKJAK3HDAC6 | |
| SCHEMBL29729087 | 0.81 | BTK (0.50) | TTBK1TTBK2BTKJAK3HDAC6 | |
| SCHEMBL1231308 | 0.80 | MAP3K14 (0.43) | TTBK1TTBK2JAK3RET | |
| SCHEMBL23409023 | 0.78 | GAA (0.57) | TTBK1TTBK2BTKPTK2HDAC6 | |
| SCHEMBL25069052 | 0.76 | JAK3 (0.42) | TTBK1TTBK2JAK3JAK1JAK2 | |
| SCHEMBL22909511 | 0.74 | TTBK1 (0.53) | TTBK1TTBK2BTKPTK2HDAC6 | |
| SCHEMBL16793608 | 0.74 | BTK (0.54) | BTKJAK3PTK2JAK1JAK2 | |
| SCHEMBL14907681 | 0.74 | NUDT1 (0.38) | BTKJAK3PTK2JAK1AAK1 | |
| SCHEMBL25069005 | 0.73 | TTBK1 (0.52) | TTBK1TTBK2BTKPTK2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | TTBK1 3603/4885TTBK2 2919/4885BTK 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.