Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 7/20 | 0.53 |
| ▸ | TTBK2 | Q6IQ55 | 7/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409023 | 0.87 | GAA (0.57) | TTBK1TTBK2PTK2IRAK4BTK | |
| SCHEMBL25069005 | 0.82 | TTBK1 (0.52) | TTBK1TTBK2PTK2IRAK4BTK | |
| SCHEMBL27545719 | 0.82 | TTBK1 (0.54) | TTBK1TTBK2PTK2IRAK4BTK | |
| SCHEMBL23409028 | 0.81 | TTBK1 (0.59) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL16266363 | 0.79 | TTBK1 (0.61) | TTBK1TTBK2BTKHDAC6TNNI3K | |
| SCHEMBL23409027 | 0.77 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL22909512 | 0.75 | TTBK1 (0.57) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL16266488 | 0.75 | LDHA (0.58) | TTBK1TTBK2BTKHDAC6 | |
| SCHEMBL8469366 | 0.75 | S1PR2 (0.57) | TTBK1TTBK2BTKHDAC6TNNI3K | |
| SCHEMBL23408985 | 0.74 | TTBK1 (0.47) | TTBK1TTBK2PTK2BTKHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |