Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | CDK7 | P50613 | 8/20 | 0.48 |
| ▸ | CDK9 | P50750 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408943 | 0.87 | MAPK1 (0.67) | MAPK3MAPK1CDK7CDK9KCNH2 | |
| SCHEMBL25068863 | 0.84 | MAPK3 (0.66) | MAPK3MAPK1CDK7CDK9KCNH2 | |
| SCHEMBL25068958 | 0.84 | MAPK1 (0.64) | MAPK3MAPK1CDK7CDK9KCNH2 | |
| SCHEMBL25068864 | 0.84 | MAPK3 (0.64) | MAPK3MAPK1CDK7CDK9KCNH2 | |
| SCHEMBL29499572 | 0.81 | MAPK1 (0.56) | MAPK3MAPK1CDK7CDK9PTK2 | |
| SCHEMBL28744841 | 0.81 | MAPK1 (0.56) | MAPK3MAPK1CDK7CDK9PTK2 | |
| SCHEMBL23409081 | 0.78 | MAPK1 (0.52) | MAPK3MAPK1CDK7CDK9PIK3CD | |
| SCHEMBL23388552 | 0.78 | MAPK3 (0.63) | MAPK3MAPK1CDK7CDK9PTK2 | |
| SCHEMBL16695821 | 0.77 | MAPK1 (0.45) | MAPK3MAPK1 | |
| SCHEMBL23408957 | 0.74 | MAPK1 (0.53) | MAPK3MAPK1CDK7CDK9PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | MAPK3 3458/4885MAPK1 4417/4885CDK7 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.