Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 5/20 | 0.47 |
| ▸ | CDK9 | P50750 | 4/20 | 0.47 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499572 | 1.00 | MAPK1 (0.56) | MAPK1MAPK3PLK4ULK1ULK2 | |
| SCHEMBL23409081 | 0.85 | MAPK1 (0.52) | MAPK1MAPK3PLK4CTSCCDK7 | |
| SCHEMBL23408957 | 0.81 | MAPK1 (0.53) | MAPK1MAPK3CTSCPTK2CDK7 | |
| SCHEMBL23409118 | 0.81 | MAPK3 (0.67) | MAPK1MAPK3ULK1PTK2CDK7 | |
| SCHEMBL28744909 | 0.80 | MAPK1 (0.50) | MAPK1MAPK3PLK4 | |
| SCHEMBL29499586 | 0.80 | MAPK1 (0.50) | MAPK1MAPK3PLK4 | |
| SCHEMBL28744926 | 0.79 | PLK4 (0.51) | MAPK1MAPK3PLK4 | |
| SCHEMBL29499595 | 0.79 | PLK4 (0.51) | MAPK1MAPK3PLK4 | |
| SCHEMBL25068865 | 0.78 | MAPK1 (0.51) | MAPK1MAPK3CTSCCDK7CDK9 | |
| SCHEMBL23408943 | 0.76 | MAPK1 (0.67) | MAPK1MAPK3PTK2CDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276331-B | 4-aminopiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114276331-A | 4-aminopiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2022-04-05 | — | — | CN | disclosed |