Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.67 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | CDK9 | P50750 | 8/20 | 0.50 |
| ▸ | CCNK | O75909 | 3/20 | 0.50 |
| ▸ | CCND3 | P30281 | 3/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.50 |
| ▸ | CDK7 | P50613 | 6/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409118 | 0.87 | MAPK3 (0.67) | MAPK1MAPK3CDK9CDK7PTK2 | |
| SCHEMBL25068863 | 0.86 | MAPK3 (0.66) | MAPK1MAPK3CDK9CDK7PTK2 | |
| SCHEMBL25068864 | 0.86 | MAPK3 (0.64) | MAPK1MAPK3CCNA2CDK2CDK9 | |
| SCHEMBL25068958 | 0.86 | MAPK1 (0.64) | MAPK1MAPK3CCNA2CDK2CDK9 | |
| SCHEMBL24867263 | 0.82 | MAPK1 (0.56) | MAPK1MAPK3AOC3KCNH2 | |
| SCHEMBL23408957 | 0.78 | MAPK1 (0.53) | MAPK1MAPK3CDK9CDK7PTK2 | |
| SCHEMBL23388552 | 0.78 | MAPK3 (0.63) | MAPK1MAPK3CDK9CDK7PTK2 | |
| SCHEMBL30394867 | 0.78 | CDK9 (0.65) | MAPK1MAPK3CCNA2CDK2CDK9 | |
| SCHEMBL29499572 | 0.76 | MAPK1 (0.56) | MAPK1MAPK3CDK9CDK7PTK2 | |
| SCHEMBL28744841 | 0.76 | MAPK1 (0.56) | MAPK1MAPK3CDK9CDK7PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |