Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409644 | 0.82 | MAPT (0.39) | CYP11B1CYP11B2KMT2ATDP1CYP19A1 | |
| SCHEMBL7132234 | 0.79 | CA12 (0.40) | SRD5A1KMT2A | |
| SCHEMBL23409641 | 0.79 | OPRM1 (0.37) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409221 | 0.74 | POLB (0.42) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409730 | 0.73 | POLB (0.41) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL23409630 | 0.73 | CYP11B1 (0.35) | CYP11B1CYP11B2KMT2ATDP1 | |
| SCHEMBL18823656 | 0.71 | CES1 (0.47) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL18823657 | 0.68 | NPC1 (0.55) | — | |
| SCHEMBL6974192 | 0.64 | ACHE (0.41) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL16790393 | 0.63 | ESR2 (0.41) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098737-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 上海枢境生物科技有限公司 | 2021-05-27 | — | — | WO | disclosed |