Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329052 | 0.83 | HMGCR (0.36) | ALDH1A1MMP8ARGAASMN1; SMN2 | |
| SCHEMBL1782336 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL8495466 | 0.72 | TSHR (0.43) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL3565109 | 0.72 | TSHR (0.43) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL3248330 | 0.72 | TSHR (0.43) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL8633404 | 0.70 | AR (0.33) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL17037419 | 0.70 | AR (0.33) | ALDH1A1TDP1MMP8ARGAA | |
| SCHEMBL11787653 | 0.70 | HTT (0.37) | ALDH1A1TDP1GAAPIK3CDMGAM | |
| Acetoacetic Acid SCHEMBL28678053 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TDP1MMP8 | |
| SCHEMBL20377190 | 0.68 | MGAM (0.40) | ALDH1A1TDP1MMP8GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534144-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098553-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2011-08-18 | — | — | WO | disclosed |