Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037419 | 1.00 | AR (0.33) | ARMMP8GRM2GRM3FDPS | |
| SCHEMBL4552961 | 0.83 | CYP1A2 (0.35) | FDPS | |
| SCHEMBL12308676 | 0.80 | MMP8 (0.33) | MMP8GRM2GRM3CYP2C19SLC7A5 | |
| SCHEMBL3565109 | 0.77 | TSHR (0.43) | ARMMP8GRM2GRM3CYP2C19 | |
| SCHEMBL3248330 | 0.77 | TSHR (0.43) | ARMMP8GRM2GRM3CYP2C19 | |
| SCHEMBL8495466 | 0.77 | TSHR (0.43) | ARMMP8GRM2GRM3CYP2C19 | |
| SCHEMBL3718753 | 0.77 | MMP8 (0.34) | MMP8GRM2GRM3CYP2C19SLC7A5 | |
| SCHEMBL4659753 | 0.77 | MMP8 (0.34) | MMP8GRM2GRM3CYP2C19SLC7A5 | |
| SCHEMBL28743867 | 0.77 | FDPS (0.33) | MMP8GRM2GRM3FDPSCYP2C19 | |
| SCHEMBL1782336 | 0.77 | ALDH1A1 (0.38) | ARMMP8CYP2C19ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |