Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 6/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | NRP1 | O14786 | 1/20 | 0.36 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694547 | 0.77 | NRP1 (0.46) | GRB2XIAPNRP1 | |
| SCHEMBL24668333 | 0.74 | GRB2 (0.38) | GRB2XIAPNRP1 | |
| SCHEMBL22209499 | 0.71 | MALT1 (0.51) | GRB2XIAP | |
| SCHEMBL24716410 | 0.71 | NRP1 (0.45) | GRB2XIAPNRP1 | |
| SCHEMBL29802139 | 0.71 | F2 (0.49) | GRB2XIAPACENRP1NTSR2 | |
| SCHEMBL29571867 | 0.70 | F2 (0.46) | GRB2XIAPACENRP1NTSR2 | |
| SCHEMBL31034448 | 0.70 | NRP1 (0.46) | GRB2NRP1NTSR2NTSR1SORT1 | |
| SCHEMBL29801986 | 0.70 | NTSR2 (0.49) | GRB2ACENRP1NTSR2NTSR1 | |
| SCHEMBL29802257 | 0.70 | NRP1 (0.53) | GRB2XIAPACENRP1NTSR2 | |
| SCHEMBL29802247 | 0.70 | NTSR2 (0.49) | GRB2ACENRP1NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |