Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | NRP1 | O14786 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694557 | 0.88 | OPRM1 (0.43) | GRB2NRP1OPRM1OPRK1 | |
| SCHEMBL30404662 | 0.80 | OPRM1 (0.48) | NRP1OPRM1OPRK1APLNR | |
| SCHEMBL29802139 | 0.79 | F2 (0.49) | GRB2XIAPNRP1OPRM1 | |
| SCHEMBL29802185 | 0.78 | ACE (0.50) | OPRK1APLNR | |
| SCHEMBL22803172 | 0.77 | OPRM1 (0.43) | NRP1OPRM1OPRK1 | |
| SCHEMBL29974998 | 0.77 | ACE (0.49) | GRB2XIAPNRP1 | |
| SCHEMBL29802048 | 0.76 | GRB2 (0.52) | GRB2XIAPNRP1OPRM1 | |
| SCHEMBL10297469 | 0.76 | XIAP (0.43) | XIAP | |
| SCHEMBL10297432 | 0.76 | XIAP (0.43) | XIAP | |
| SCHEMBL23417888 | 0.74 | GRB2 (0.42) | GRB2XIAPNRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |