SCHEMBL29802257

SCHEMBL29802257

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NRP1 O14786 2/20 0.53
F2 P00734 1/20 0.52
NTSR2 O95665 7/20 0.48
NTSR1 P30989 7/20 0.48
SORT1 Q99523 5/20 0.48
DPP4 P27487 2/20 0.48
DPP8 Q6V1X1 2/20 0.48
DPP9 Q86TI2 2/20 0.48
DPP7 Q9UHL4 2/20 0.48
FAP Q12884 1/20 0.48
OPRM1 P35372 1/20 0.48
ACE P12821 3/20 0.46
GRB2 P62993 1/20 0.46
XIAP P98170 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29801929 0.96 GRB2 (0.51) NRP1F2NTSR2NTSR1SORT1
SCHEMBL31039951 0.93 OPRM1 (0.56) NRP1F2NTSR2NTSR1SORT1
SCHEMBL29802247 0.93 NTSR2 (0.49) NRP1F2NTSR2NTSR1SORT1
SCHEMBL29802139 0.93 F2 (0.49) NRP1F2NTSR2NTSR1SORT1
SCHEMBL29802410 0.92 ACE (0.49) NRP1F2NTSR2NTSR1SORT1
SCHEMBL29571627 0.91 NRP1 (0.54) NRP1F2NTSR2NTSR1SORT1
SCHEMBL30997450 0.91 GRB2 (0.55) NRP1F2NTSR2NTSR1SORT1
SCHEMBL29802012 0.91 ACE (0.48) NRP1F2NTSR2NTSR1OPRM1
SCHEMBL31519056 0.91 F2 (0.58) F2NTSR2NTSR1SORT1DPP4
SCHEMBL8601713 0.91 DPP7 (0.53) NRP1F2NTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306534-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES Wuhan Innerse Pharmaceutical Inc. (CN) 2024-01-17 EP disclosed
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SHANGHAI LUMOSA THERAPEUTICS CO LTD (CN) 2023-10-05 US disclosed
WO-2022188878-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES 武汉英纳氏药业有限公司 2022-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SERPINC1, PLAT, F2 NRP1 2622/4885F2 3/4885NTSR2 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.