Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28706002 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28861859 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9768549 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9484769 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL108476 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472621-A2 | WEAR-RESISTANT COMPOSITIONS INCLUDING CROSSLINKED AROMATIC POLYMERS AND METHODS FOR IMPROVING WEAR RESISTANCE USING THE SAME | Greene, Tweed Technologies, Inc. (US) | 2024-12-11 | — | — | EP | claimed |
| CN-118320165-A | Preparation method of boron-containing nanosheet antibacterial dressing | 大连理工大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118063859-A | Preparation method of high-dispersion nano silicon dioxide composite material | 扬州德鲁克科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117417662-A | Method for doping germanium into composite light stabilizer | 孝感博镧铕新材料有限公司 | 2024-01-19 | — | — | CN | claimed |
| US-20230407157-A1 | Wear-Resistant Compositions Including Crosslinked Aromatic Polymers and Methods for Improving Wear Resistance Using the Same | GREENE, TWEED TECHNOLOGIES, INC. | 2023-12-21 | — | — | US | claimed |
| US-20230381069-A1 | TOPICAL COMPOSITIONS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2023-11-30 | — | — | US | claimed |
| WO-2023150723-A2 | WEAR-RESISTANT COMPOSITIONS INCLUDING CROSSLINKED AROMATIC POLYMERS AND METHODS FOR IMPROVING WEAR RESISTANCE USING THE SAME | GREENE, TWEED TECHNOLOGIES, INC. (US) | 2023-08-10 | — | — | WO | claimed |
| WO-2023150732-A2 | END EFFECTORS AND END EFFECTOR PADS HAVING CROSSLINKED POLYMERS FOR SEMICONDUCTOR APPLICATIONS TO PROVIDE IMPROVED MANUFACTURING SPEED AND METHODS OF MAKING AND USING THE SAME | GREENE, TWEED TECHNOLOGIES, INC. (US) | 2023-08-10 | — | — | WO | claimed |
| CN-115418025-B | Protective material for rubber and plastic and preparation method thereof | 常州市五洲环保科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-116376467-A | LCM silver colloid preparation method | 北京中科纳通电子技术有限公司 | 2023-07-04 | — | — | CN | claimed |
| EP-1212277-B1 | AN INTEGRATED PROCESS FOR THE PRODUCTION OF 2,6-NAPHTHALENE DICARBOXYLIC ACID | MOSSI & GHISOLFI INT SA (LU) | 2004-04-21 | — | — | EP | claimed |
| US-20030032339-A1 | Method of producing electrical connectors for use in downhole tools and electrical connector produced thereby | GREENE, TWEED OF DELAWARE, INC. | 2003-02-13 | — | — | US | claimed |
| US-20020195739-A1 | Method for producing sealing and anti-extrusion components for use in downhole tools and components produced thereby | GREENE, TWEED OF DELAWARE, INC. | 2002-12-26 | — | — | US | claimed |
| WO-2002079606-A1 | METHOD FOR PRODUCING SEALING AND ANTI-EXTRUSION COMPONENTS FOR USE IN DOWNHOLE TOOLS AND COMPONENTS PRODUCED THEREBY | GREENE, TWEED OF DELEWARE, INC. (US) | 2002-10-10 | — | — | WO | claimed |
| WO-2002078946-A1 | ELECTRICAL CONNECTORS FOR USE IN DOWNHOLE TOOLS | GREENE, TWEED OF DELAWARE, INC. (US) | 2002-10-10 | — | — | WO | claimed |
| US-6448436-B1 | RELATIVELY IMPURE METHYLNAPHTHALENE REACTANT; DEBROMINATION OF THE OXIDATION PRODUCT IN THE LIQUID PHASE, AND AVOIDS THE ISOLATION OF PURIFIED NAPHTHOIC ACID | MOSSI & GHISOLFI OVERSEAS, S. A. (LU) | 2002-09-10 | — | — | US | claimed |
| EP-1212277-A2 | AN INTEGRATED PROCESS FOR THE PRODUCTION OF 2,6-NAPHTHALENE DICARBOXYLIC ACID | Mossi & Ghisolfi Overseas S.A. (LU) | 2002-06-12 | — | — | EP | claimed |
| WO-2001016074-A2 | AN INTEGRATED PROCESS FOR THE PRODUCTION OF 2,6-NAPHTHALENE DICARBOXYLIC ACID | MOSSI & GHISOLFI OVERSEAS S.A. (LU) | 2001-03-08 | — | — | WO | claimed |
| US-4198458-A | MAGNETIC TAPES | TEIJIN LIMITED (JP) | 1980-04-15 | — | — | US | claimed |
| US-3996142-A | Smoke and fire retardants for halogen-containing plastic compositions comprising the reaction product of magnesium oxide and a zinc salt of an acid | NL INDUSTRIES, INC. (US) | 1976-12-07 | — | — | US | claimed |