Isopimaric Acid

Isopimaric Acid

SCHEMBL234276

C=C[C@@]1(C)CC[C@H]2C(=CC[C@@H]3[C@]2(C)CCC[C@@]3(C)C(=O)O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 1.00
▸ RXRB P28702 1/20 1.00
▸ RXRG P48443 1/20 1.00
▸ CYP2C9 P11712 2/20 0.58
▸ CYP2C19 P33261 2/20 0.58
▸ HSD17B10 Q99714 3/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ PDK1 Q15118 2/20 0.50
▸ PDK2 Q15119 2/20 0.50
▸ PDK3 Q15120 2/20 0.50
▸ PDK4 Q16654 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ SLCO1B3 Q9NPD5 1/20 0.50
▸ SLCO1B1 Q9Y6L6 1/20 0.50
▸ GABRA1 P14867 1/20 0.50
▸ GABRB2 P47870 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopimaric Acid SCHEMBL13702083 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15339339 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL2603438 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744757 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL12732275 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744755 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL4549113 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Sandaracopimaric Acid SCHEMBL3894069 0.89 RXRA (0.80) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL31390163 0.88 RXRA (0.78) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL17891641 0.87 RXRA (0.77) RXRARXRBRXRGCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3646 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087386-A1 ROSIN DIESTER COMPOUNDS AND USES THEREOF FIRMENICH SA (CH) 2026-04-30 — — WO claimed
EP-4457392-B1 CHEMICALLY BONDED NONWOVEN SUBSTRATES ARKEMA FRANCE (FR) 2026-04-01 — — EP claimed
US-20260085032-A1 NOVEL SURFACTANTS DERIVED FROM GLYCIDYL ESTERS OF ROSIN ACIDS LAMBERTI SPA (IT) 2026-03-26 — — US claimed
US-12577381-B2 Chloroprene polymer composition, manufacturing method therefor, and dip-molded article DENKA COMPANY LIMITED (JP) 2026-03-17 — — US claimed
US-12571046-B2 Methods of detecting and treating multiple system atrophy THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2026-03-10 — — US claimed
US-20250388772-A1 NATURAL INGREDIENT EXTERIOR WOOD PRIMER PAINT COMPOSITION SMITH DAVID L (US) 2025-12-25 — — US claimed
EP-4619459-A1 MODIFIED PU FOAM Wenatex Forschung - Entwicklung - Produktion GmbH (AT) 2025-09-24 — — EP claimed
EP-4619578-A2 MODIFIED FIBRE MATERIAL Wenatex Forschung - Entwicklung - Produktion GmbH (AT) 2025-09-24 — — EP claimed
US-12419925-B2 Feed supplement AB VISTA FINLAND OY (FI) 2025-09-23 — — US claimed
EP-4035908-B1 RESIN-MODIFIED VEGETABLE OILS IN RUBBER COMPOSITIONS AND TIRES GOODYEAR TIRE & RUBBER (US) 2025-06-25 — — EP claimed
US-5415865-A Means having microbial effect and little or completely abolished tendency to develop contact allergic reactions or toxic effects and use thereof in e.g. skin and wound treatment products MOLNLYCKE AB (SE) 1995-05-16 — — US claimed
EP-0526541-B1 MEANS HAVING MICROBIAL EFFECT AND LITTLE OR COMPLETELY ABOLISHED TENDENCY TO DEVELOP CONTACT ALLERGIC REACTIONS OR TOXIC EFFECTS AND USE THEREOF IN E.G. SKIN AND WOUND TREATMENT PRODUCTS MOELNLYCKE AB (SE) 1995-01-25 — — EP claimed
US-5360458-A Emulsifier is salt of carboxylic acid and hydroxyamine, pipeline transportation of crude oil THE LUBRIZOL CORPORATION (US) 1994-11-01 — — US claimed
EP-0567000-A1 Dicyclopentadiene alcohol rosin acid derivatives THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-10-27 — — EP claimed
US-5246998-A Rubber additive; ozone resistance THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-09-21 — — US claimed
US-5118740-A Rubber additive THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-06-02 — — US claimed
US-4996295-A Processing aid in rubber formulation THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-02-26 — — US claimed
US-4973389-A Process for making a high temperature-resistant metal layer on a ceramic surface SCHERING AKTIENGESELLSCHAFT (DE) 1990-11-27 — — US claimed
US-4507228-A AND DESULFURIZATION WESTVACO CORPORATION (US) 1985-03-26 — — US claimed
US-4238380-A Disodium ethoxylated rosin half esters of sulfosuccinic acid as foam stabilizers for latices and compositions containing same WESTVACO CORPORATION (US) 1980-12-09 — — US claimed
Send feedback