Isopimaric Acid

Isopimaric Acid

SCHEMBL4549113

C=CC1(C)CCC2C(=CCC3C(C)(C(=O)O)CCCC23C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 1.00
▸ RXRB P28702 1/20 1.00
▸ RXRG P48443 1/20 1.00
▸ CYP2C9 P11712 2/20 0.58
▸ CYP2C19 P33261 2/20 0.58
▸ HSD17B10 Q99714 3/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ PDK1 Q15118 2/20 0.50
▸ PDK2 Q15119 2/20 0.50
▸ PDK3 Q15120 2/20 0.50
▸ PDK4 Q16654 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ SLCO1B3 Q9NPD5 1/20 0.50
▸ SLCO1B1 Q9Y6L6 1/20 0.50
▸ GABRA1 P14867 1/20 0.50
▸ GABRB2 P47870 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopimaric Acid SCHEMBL234276 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL13702083 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15339339 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL2603438 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744757 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL12732275 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744755 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Sandaracopimaric Acid SCHEMBL3894069 0.89 RXRA (0.80) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL31390163 0.88 RXRA (0.78) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL17891641 0.87 RXRA (0.77) RXRARXRBRXRGCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802099-B2 Or relating to energetic materials LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) 2023-10-31 — — US disclosed
US-11802099-B2 Or relating to energetic materials LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) 2023-10-31 — — US disclosed
US-20220195348-A1 TREATMENT COMPOSITIONS COMPRISING PLANT ROSIN MATERIAL AND CERTAIN PERFUME RAW MATERIALS THE PROCTER & GAMBLE COMPANY 2022-06-23 — — US disclosed
US-20220186147-A1 LIQUID TREATMENT COMPOSITIONS COMPRISING DELIVERY PARTICLES BASED ON PLANT ROSIN MATERIAL THE PROCTER & GAMBLE COMPANY 2022-06-16 — — US disclosed
US-20220186149-A1 TREATMENT COMPOSITIONS COMPRISING CERTAIN PLANT ROSIN MATERIALS THE PROCTER & GAMBLE COMPANY 2022-06-16 — — US disclosed
US-20220186148-A1 PROCESS OF MAKING A TREATMENT COMPOSITION THAT INCLUDES A PLANT ROSIN MATERIAL AND RELATED PREMIX COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2022-06-16 — — US disclosed
US-20200148609-A1 IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) 2020-05-14 — — US disclosed
US-10442955-B2 Resin, composition and use DSM IP ASSETS B.V. (NL) 2019-10-15 — — US disclosed
EP-3367170-B1 TONER COMPOSITIONS XEROX CORP (US) 2019-09-25 — — EP disclosed
US-20180142121-A1 RESIN, COMPOSITION AND USE COVESTRO (NETHERLANDS) B.V. (NL) 2018-05-24 — — US disclosed
US-20120183896-A1 Rosin-Based Resin and Toner Containing Same XEROX CORPORATION (US) 2012-07-19 — — US disclosed
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION Aristotle University of Thessalokiki (GR) 2012-05-10 — — US disclosed
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION Aristotle University of Thessalokiki (GR) 2012-05-10 — — US disclosed
US-20110269867-A1 ALKALI-SOLUBLE POLYMER COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME LG CHEM. LTD. (KR) 2011-11-03 — — US disclosed
US-20110269867-A1 ALKALI-SOLUBLE POLYMER COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME LG CHEM. LTD. (KR) 2011-11-03 — — US disclosed
US-20110135922-A1 Adhesive Compositions with Multiple Tackifiers 3M INNOVATIVE PROPERTIES COMPANY 2011-06-09 — — US disclosed
US-20110135922-A1 Adhesive Compositions with Multiple Tackifiers 3M INNOVATIVE PROPERTIES COMPANY 2011-06-09 — — US disclosed
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION ARISTOTLE UNIVERSITY OF THESSALONIKI (GR) 2011-02-24 — — US disclosed
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION ARISTOTLE UNIVERSITY OF THESSALONIKI (GR) 2011-02-24 — — US disclosed
WO-2009146227-A1 ADHESIVE COMPOSITIONS WITH MULTIPLE TACKIFIERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION LARP1, LARP7, TNF RXRA 2300/4885RXRB 2892/4885RXRG 2310/4885
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION LARP1, LARP7, TNF RXRA 1970/4885RXRB 2591/4885RXRG 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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