Isopimaric Acid

Isopimaric Acid

SCHEMBL2603438

C=C[C@@]1(C)CCC2C(=CCC3[C@]2(C)CCC[C@@]3(C)C(=O)O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 1.00
▸ RXRB P28702 1/20 1.00
▸ RXRG P48443 1/20 1.00
▸ CYP2C9 P11712 2/20 0.58
▸ CYP2C19 P33261 2/20 0.58
▸ HSD17B10 Q99714 3/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ PDK1 Q15118 2/20 0.50
▸ PDK2 Q15119 2/20 0.50
▸ PDK3 Q15120 2/20 0.50
▸ PDK4 Q16654 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ SLCO1B3 Q9NPD5 1/20 0.50
▸ SLCO1B1 Q9Y6L6 1/20 0.50
▸ GABRA1 P14867 1/20 0.50
▸ GABRB2 P47870 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopimaric Acid SCHEMBL234276 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL13702083 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15339339 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744757 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL12732275 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL15744755 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Isopimaric Acid SCHEMBL4549113 1.00 RXRA (1.00) RXRARXRBRXRGCYP2C9CYP2C19
Sandaracopimaric Acid SCHEMBL3894069 0.89 RXRA (0.80) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL31390163 0.88 RXRA (0.78) RXRARXRBRXRGCYP2C9CYP2C19
SCHEMBL17891641 0.87 RXRA (0.77) RXRARXRBRXRGCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3075787-B1 PIGMENT DISPERSION AND PRODUCING METHOD THEREOF FUJIFILM CORP (JP) 2023-06-07 — — EP disclosed
US-10280329-B2 Pigment dispersion and producing method thereof FUJIFILM CORPORATION (JP) 2019-05-07 — — US disclosed
EP-2857391-B1 LABDANE DITERPENOID COMPOUNDS, SEMEN BIOTAE EXTRACT, AND PREPARATION METHOD AND USE THEREOF UNIV SUN YAT SEN (CN) 2017-07-19 — — EP disclosed
US-9682111-B2 Method for preventing or treating neurodegenerative diseases SU WEIWEI (CN) 2017-06-20 — — US disclosed
US-20160289486-A1 PIGMENT DISPERSION AND PRODUCING METHOD THEREOF FUJIFILM CORPORATION (JP) 2016-10-06 — — US disclosed
US-20160289486-A1 PIGMENT DISPERSION AND PRODUCING METHOD THEREOF FUJIFILM CORPORATION (JP) 2016-10-06 — — US disclosed
EP-3075787-A1 PIGMENT DISPERSION AND PRODUCING METHOD THEREOF FUJIFILM Corporation (JP) 2016-10-05 — — EP disclosed
US-20160082059-A1 METHOD FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES SU WEIWEI (CN) 2016-03-24 — — US disclosed
US-20150105460-A1 LABDANE DITERPENOID COMPOUNDS, SEMEN BIOTAE EXTRACT, AND PREPARATION METHOD AND USE THEREOF SU WEIWEI (CN) 2015-04-16 — — US disclosed
EP-2857391-A1 LABDANE DITERPENOID COMPOUNDS, SEMEN BIOTAE EXTRACT, AND PREPARATION METHOD AND USE THEREOF Sun Yat-Sen University (CN) 2015-04-08 — — EP disclosed
US-8748561-B2 Dehydroabietic acid polymer, compact, method for producing dehydroabietic acid polymer, and dehydroabietic acid compound FUJIFILM CORPORATION (JP) 2014-06-10 — — US disclosed
US-20130022907-A1 POLYMER DERIVED FROM DEHYDROABIETIC ACID AND USES THEREOF FUJIFILM CORPORATION (JP) 2013-01-24 — — US disclosed
US-20120322969-A1 DEHYDROABIETIC ACID POLYMER, COMPACT, METHOD FOR PRODUCING DEHYDROABIETIC ACID POLYMER, AND DEHYDROABIETIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2012-12-20 — — US disclosed
US-20120101250-A1 NOVEL DEHYDROABIETIC ACID POLYMER FUJIFILM CORPORATION (JP) 2012-04-26 — — US disclosed
US-7825162-B2 Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-11-02 — — US disclosed
US-7820212-B2 Abietane diterpenoid compound, and composition comprising extract of Torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-10-26 — — US disclosed
US-7517542-B2 Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease KOREA RESEARCH INSTITUTE OF BIOSCIENCE (KR) 2009-04-14 — — US disclosed
US-20090062384-A1 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2009-03-05 — — US disclosed
US-20080299238-A1 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-04 — — US disclosed
US-20070190192-A1 Novel abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND (KR) 2007-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299238-A1 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE ACAT1, ACAT2, LCAT RXRA 666/4885RXRB 1407/4885RXRG 1504/4885
US-20150105460-A1 LABDANE DITERPENOID COMPOUNDS, SEMEN BIOTAE EXTRACT, AND PREPARATION METHOD AND USE THEREOF NASP, GSDMD, DRD5 RXRA 3283/4885RXRB 4080/4885RXRG 4093/4885
US-20120322969-A1 DEHYDROABIETIC ACID POLYMER, COMPACT, METHOD FOR PRODUCING DEHYDROABIETIC ACID POLYMER, AND DEHYDROABIETIC ACID COMPOUND DDOST, DHPS, DAD1 RXRA 823/4885RXRB 1273/4885RXRG 1435/4885
US-20160082059-A1 METHOD FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES SNCA, HTT, PARK7 RXRA 3439/4885RXRB 4005/4885RXRG 3901/4885
US-20090062384-A1 NOVEL ABIETANE DITERPENOID COMPOUND, AND COMPOSITION COMPRISING EXTRACT OF TORREYA NUCIFERA, OR ABIETANE DITERPENOID COMPOUNDS OR TERPENOID COMPOUNDS ISOLATED FROM THEM FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE ACAT1, ACAT2, LCAT RXRA 1015/4885RXRB 1771/4885RXRG 1907/4885
US-20070190192-A1 Novel abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease ACAT1, ACAT2, LCAT RXRA 666/4885RXRB 1407/4885RXRG 1504/4885
US-20120101250-A1 NOVEL DEHYDROABIETIC ACID POLYMER DPAGT1, DDOST, ALAD RXRA 375/4885RXRB 447/4885RXRG 568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback