SCHEMBL23428271

SCHEMBL23428271

c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4ccc5c(c4)sc4c(-c6c7ccccc7c(-c7cc(-c8ccccc8)cc(-c8ccccc8)c7)c7ccccc67)cccc45)c4ccccc34)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
LIMK1 P53667 11/20 0.39
PRKDC P78527 3/20 0.34
PARP14 Q460N5 1/20 0.34
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
F9 P00740 1/20 0.33
LIMK2 P53671 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23427789 0.99 ALOX5 (0.44) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23428008 0.99 ALOX5 (0.44) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23428273 0.96 ALOX5 (0.46) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23427787 0.94 ALOX5 (0.45) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23427459 0.94 ALOX5 (0.45) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23428254 0.93 ALOX5 (0.48) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23428067 0.90 ALOX5 (0.52) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23426738 0.90 ALOX5 (0.52) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL21131674 0.90 ALOX5 (0.51) ALOX5LIMK1PRKDCPARP14TNKS
SCHEMBL23427817 0.89 ALOX5 (0.45) ALOX5LIMK1PRKDCPARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11991927-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 US disclosed
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20210249610-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-08-12 US disclosed
US-20210167299-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210167299-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, AOX1, OXER1 ALOX5 1296/4885LIMK1 515/4885PRKDC 4745/4885
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP2E1, AOX1 ALOX5 978/4885LIMK1 233/4885PRKDC 4006/4885
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 ALOX5 894/4885LIMK1 285/4885PRKDC 4518/4885
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 ALOX5 794/4885LIMK1 322/4885PRKDC 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.