Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865638 | 0.94 | CHRM2 (0.46) | SCN8ACHRM2HRH4HRH3SMN1; SMN2 | |
| SCHEMBL4620705 | 0.85 | SCN8A (0.42) | SCN8ACHRM2SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL2082460 | 0.84 | NOS3 (0.45) | SCN8ANPC1HTTADORA2AADORA1 | |
| SCHEMBL2261106 | 0.82 | NOS3 (0.41) | NPC1ADORA2AADORA1L3MBTL1 | |
| SCHEMBL20281240 | 0.82 | SMN1; SMN2 (0.46) | SCN8ACHRM2NPC1HRH4HRH3 | |
| SCHEMBL20482639 | 0.80 | ADORA2A (0.45) | SCN8ACHRM2NPC1SMN1; SMN2HTT | |
| SCHEMBL16268934 | 0.79 | OPRM1 (0.41) | SCN8ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL16268932 | 0.79 | CYP2C19 (0.45) | SCN8ASMN1; SMN2 | |
| SCHEMBL26027287 | 0.78 | SCN8A (0.37) | SCN8ACHRM2NPC1SMN1; SMN2ADORA2A | |
| SCHEMBL8582607 | 0.77 | L3MBTL1 (0.43) | NPC1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |