SCHEMBL2342977

SCHEMBL2342977

CCCc1ccccc1.O=S(=O)(Cl)Cl

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.50
CNR2 P34972 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
POLB P06746 1/20 0.46
TP53 P04637 1/20 0.44
CA1 P00915 1/20 0.44
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 4/20 0.43
PSIP1 O75475 1/20 0.43
SIGMAR1 Q99720 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
BLM P54132 1/20 0.42
GFER P55789 1/20 0.42
PMP22 Q01453 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylbenzyl SCHEMBL2342999 0.87 CA2 (0.53) CA2CNR2MEN1KMT2APOLB
Sulfuric Acid SCHEMBL9751311 0.86 ALDH1A1 (0.57) CA2CNR2MEN1KMT2APOLB
SCHEMBL11580921 0.85 CA2 (0.50) CA2CA1CA9ALDH1A1KDM4E
SCHEMBL40575 0.85
Benzene SCHEMBL28308118 0.85 TP53 (0.58) TP53ALDH1A1SIGMAR1HPGDALOX15
SCHEMBL11594885 0.85 TP53 (0.58) TP53ALDH1A1SIGMAR1HPGDALOX15
SCHEMBL19980741 0.85 ALDH1A1 (0.58) CA2CNR2MEN1KMT2AALDH1A1
Benzene SCHEMBL3223041 0.85 TP53 (0.58) TP53ALDH1A1SIGMAR1HPGDALOX15
SCHEMBL27510222 0.85 MEN1 (0.56) CA2CNR2MEN1KMT2APOLB
SCHEMBL11412978 0.84 KCNH2 (0.59) CA2MEN1KMT2ATP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109568479-A A kind of Traditional Chinese medicine permeation liquid and preparation method thereof for treating the proliferation of mammary gland 义乌凌川科技有限公司 2019-04-05 CN claimed
CN-108863870-A A kind of preparation method of alkyl substituted benzene thiophenol 天津瑞岭化工有限公司 2018-11-23 CN claimed
CN-103265436-A Method for synthesising 1,5,9-trinitro-2,3,6,7,10,11-hexa-alkoxy triphenylene UNIV SHAANXI NORMAL 2013-08-28 CN claimed
CN-101100461-B Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof PENGCHENG REN 2012-04-18 CN claimed
CN-101100461-A Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof PENGCHENG REN (CN) 2008-01-09 CN claimed
CN-108863870-A A kind of preparation method of alkyl substituted benzene thiophenol 天津瑞岭化工有限公司 2018-11-23 CN disclosed
CN-108350018-A The manufacturing method of oligonucleotides 日产化学工业株式会社 2018-07-31 CN disclosed
CN-105777545-B A kind of preparation method of alpha-fluoro acrylic ester 衢州福瑞凯化工科技有限公司 2018-06-12 CN disclosed
CN-103351465-B Photoresist material monomer, photoresist material and their preparation method, colored filter BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-09-09 CN disclosed
CN-103265436-B Method for synthesising 1,5,9-trinitro-2,3,6,7,10,11-hexa-alkoxy triphenylene UNIV SHAANXI NORMAL 2015-03-18 CN disclosed
CN-104220421-A Sulfonamide derivatives of benzylamine for the treatment of central nervous system disorders ADAMED SP ZOO 2014-12-17 CN disclosed
CN-103922977-A Novel method for preparing sulfonyl quinones UNIV JIANGNAN 2014-07-16 CN disclosed
WO-2003070244-A1 ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES ABBOTT LABORATORIES (US) 2003-08-28 WO disclosed
CN-1438997-A Inhibitors of 11-beta-hydroxy steroid dehydrogenase type I BIOVITRUM AB (SE) 2003-08-27 CN disclosed
CN-1437588-A 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors BIOVITRUM AB (SE) 2003-08-20 CN disclosed
CN-1430615-A Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 BIOVITRUM AB (SE) 2003-07-16 CN disclosed
CN-1430614-A Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 BIOVITRUM AB (SE) 2003-07-16 CN disclosed
CN-1283189-A Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors DIMENSIONAL PHARM INC (US) 2001-02-07 CN disclosed
CN-1281451-A Benzamidine derivatives MERCK PATENT GMBH (DE) 2001-01-24 CN disclosed
CN-1272107-A Benzamidine derivatives as factor Xa inhibitors MERCK PATENT GMBH (DE) 2000-11-01 CN disclosed