Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23405498 | 0.88 | MAPT (0.54) | SNCAMAPTRAC1POLBPKM | |
| SCHEMBL23405475 | 0.75 | MAPT (0.67) | SNCAMAPTNPC1CYP1B1STIM1 | |
| SCHEMBL23405471 | 0.74 | SNCA (0.62) | SNCAMAPTGFERNPC1POLB | |
| SCHEMBL22340587 | 0.74 | BCHE (0.49) | NPC1KMT2ACA1CA2CA5A | |
| SCHEMBL23405493 | 0.72 | SNCA (0.59) | SNCAMAPTGFERPOLBPKM | |
| SCHEMBL12682333 | 0.71 | SNCA (1.00) | SNCAMAPTCYP1B1ESRRGCA1 | |
| SCHEMBL23405476 | 0.71 | MAPT (0.81) | SNCAMAPTGFERNPC1POLB | |
| SCHEMBL23405500 | 0.70 | SNCA (0.61) | SNCAMAPTGFERGAAKMT2A | |
| SCHEMBL26628340 | 0.70 | STIM1 (0.67) | SNCASTIM1ORAI1 | |
| SCHEMBL23405495 | 0.69 | MAPT (0.82) | SNCAMAPTESRRGCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | FABP4, LIPC, GPR119 | SNCA 4775/4885MAPT 2951/4885RAC1 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.