Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.30 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.30 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.30 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.30 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23071798 | 0.89 | MGLL (0.37) | NPC1RAB9ASMN1; SMN2NAMPTS1PR1 | |
| SCHEMBL23432977 | 0.86 | MEN1 (0.33) | NPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL20402344 | 0.86 | CA12 (0.36) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL23961617 | 0.86 | CA12 (0.36) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL20402342 | 0.85 | NAMPT (0.40) | NPC1RAB9ASMN1; SMN2NAMPTS1PR1 | |
| SCHEMBL23071957 | 0.84 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2S1PR1ROCK1 | |
| SCHEMBL24087858 | 0.83 | OPRK1 (0.35) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL23071941 | 0.82 | CA12 (0.40) | NPC1RAB9ASMN1; SMN2S1PR1CA12 | |
| SCHEMBL19026314 | 0.79 | CA12 (0.36) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL22147094 | 0.78 | KMT2A (0.41) | RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163458-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI SA (FR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163458-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | XPOT, HCCS, COIL | NPC1 15/4885RAB9A 1424/4885SMN1; SMN2 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.