⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463497 | 0.86 | KDM4E (0.46) | — | |
| SCHEMBL10670706 | 0.83 | KDM4E (0.55) | — | |
| SCHEMBL31452231 | 0.81 | ALDH1A1 (0.53) | — | |
| SCHEMBL10684352 | 0.79 | KDM4E (0.51) | — | |
| SCHEMBL2224090 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL3797836 | 0.78 | KDM4E (0.54) | — | |
| SCHEMBL12518240 | 0.78 | HCAR3 (0.50) | — | |
| SCHEMBL1462344 | 0.77 | — | — | |
| SCHEMBL14067217 | 0.77 | — | — | |
| SCHEMBL19555075 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| EP-4105207-A1 | QUINOLYL PHOSPHINE OXIDE COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2022-12-21 | — | — | EP | disclosed |
| US-20210038607-A1 | OXADIAZOLYLTHIOPHENE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | KARUS THERAPEUTICS LIMITED (GB) | 2021-02-11 | — | — | US | disclosed |
| US-10752639-B2 | Bridged bicyclic inhibitors of menin-MLL and methods of use | KURA ONCOLOGY, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190092783-A1 | BRIDGED BICYCLIC INHIBITORS OF MENIN-MLL AND METHODS OF USE | KURA ONCOLOGY, INC. (US) | 2019-03-28 | — | — | US | disclosed |
| EP-3083619-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | Asana BioSciences, LLC (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2016145417-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2015095128-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES, LLC (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-2471787-A1 | New compounds | Boehringer Ingelheim International GmbH (DE) | 2012-07-04 | — | — | EP | disclosed |
| EP-2445889-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-05-02 | — | — | EP | disclosed |
| US-5219480-A | ETHYLENE ALPHA-OLEFIN MANNICH BASE VISCOSITY INDEX IMPROVER/DISPERSANT ADDITIVES DERIVED FROM AMINO PHENOLS AND MONOSECONDARY AMINES | EXXON CHEMICAL PATENTS INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-5019571-A | 1-carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0357215-A1 | Ethylene alpha-olefin mannich base viscosity index improver/dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4902707-A | Bicyclic pyrazolidinones, compositions and use | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4895702-A | FORMING FILMS ON METAL TOOLS AND EQUIPMENT USED IN DRILLING AND SERVICING OF GAS AND OIL WELLS; HIGH AND LOW TEMPERATURE AND PRESSURE RESISTANT | THE DOW CHEMICAL COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0203722-A1 | Bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
| CN-86102877-A | The method for preparing bicyclic pyrazolidinones | — | 1986-10-29 | — | — | CN | disclosed |
| CN-86103619-A | The preparation method of the bicyclic pyrazolidinones that 7-replaces | — | 1986-10-29 | — | — | CN | disclosed |