Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344309 | 0.98 | APP (0.37) | APPLMNAALDH1A1POLBRAB9A | |
| SCHEMBL28692737 | 0.91 | APP (0.41) | APPLMNABLMPTGS1PDE4A | |
| SCHEMBL357781 | 0.82 | PTGS1 (0.36) | APPLMNABLMPTGS1PDE4A | |
| SCHEMBL16340570 | 0.80 | APP (0.35) | APP | |
| SCHEMBL14312787 | 0.79 | DGKA (0.40) | — | |
| SCHEMBL2344305 | 0.78 | TSHR (0.40) | LMNAALDH1A1SMN1; SMN2BLMMAPT | |
| SCHEMBL22919096 | 0.75 | APP (0.38) | APPLMNABLMPTGS1PDE4A | |
| SCHEMBL419968 | 0.75 | APP (0.46) | APPLMNAALDH1A1POLBRAB9A | |
| SCHEMBL420986 | 0.75 | APP (0.46) | APPLMNAALDH1A1POLBRAB9A | |
| SCHEMBL754172 | 0.75 | APP (0.46) | APPLMNAALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105907489-A | Silicon wafer cleaning agent and method for preparing same | 安庆友仁电子有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-105907489-A | Silicon wafer cleaning agent and method for preparing same | 安庆友仁电子有限公司 | 2016-08-31 | — | — | CN | disclosed |
| US-8008358-B2 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2011-08-30 | — | — | US | disclosed |
| US-8008358-B2 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2011-08-30 | — | — | US | disclosed |
| US-8008358-B2 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-2208723-A1 | Fluorosurfactants | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-2208723-A1 | Fluorosurfactants | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-1833786-B1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1833786-B1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2010-02-17 | — | — | EP | disclosed |
| US-20080149878-A1 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| US-20080149878-A1 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| US-20080149878-A1 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | MERCK PATENT GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| EP-1833786-A1 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006072401-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080149878-A1 | having terminal pentafluorosulfuranyl group or terminal trifluoromethoxy group and also a polar end group; fully degradable substitutes for perfluorinated surfactants; paint, fire-extinguishing composition, lubricant, cleaner, deicer, hydrophobicising for textile finishing or glass treatment; emulsifier | FFAR3, PFAS, FGR | APP 3370/4885LMNA 2286/4885ALDH1A1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.