Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998920 | 0.91 | ADK (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL1684799 | 0.91 | ADK (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL24798428 | 0.88 | LMNA (0.45) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL17748441 | 0.88 | ADORA3 (0.53) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL16629487 | 0.88 | LMNA (0.50) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL21275623 | 0.88 | LMNA (0.50) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL1065626 | 0.87 | LMNA (0.44) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL5697581 | 0.86 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL5953706 | 0.86 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL6297856 | 0.86 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206935-B2 | Method of rapidly quantifying hydroxymethylated DNA | LI WEIWEI (US) | 2012-06-26 | — | — | US | disclosed |
| US-20120107808-A1 | High throughput detection of gene-specific hydroxymethylation | LI WEIWEI (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120003663-A1 | Method of rapidly quantifying hydroxymethylated DNA | LI WEIWEI (US) | 2012-01-05 | — | — | US | disclosed |