Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24033161 | 0.77 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL29134312 | 0.75 | — | — | |
| SCHEMBL30316262 | 0.75 | TSHR (0.33) | HRH3 | |
| SCHEMBL21919487 | 0.74 | CXCR4 (0.36) | HRH3SLC6A2 | |
| Hydrochloric Acid SCHEMBL20594525 | 0.72 | CXCR4 (0.35) | LMNAHRH3SLC6A2SLC6A4 | |
| SCHEMBL25001375 | 0.72 | — | — | |
| SCHEMBL17693023 | 0.72 | SLC6A2 (0.43) | LMNAHRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21919496 | 0.69 | SIGMAR1 (0.33) | — | |
| SCHEMBL21919407 | 0.69 | GPR119 (0.31) | — | |
| SCHEMBL31010083 | 0.69 | HRH3 (0.35) | LMNAHRH3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220081441-A1 | CYCLOALKYLUREA DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-03-17 | — | — | US | disclosed |
| WO-2021107023-A1 | CYCLOALKYL UREA DERIVATIVE | 大日本住友製薬株式会社 | 2021-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081441-A1 | CYCLOALKYLUREA DERIVATIVE | HCRTR2, HCRTR1, CRHR2 | LMNA 3846/4885HRH3 7/4885SLC6A2 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.