Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24033161 | 0.98 | TSHR (0.30) | TSHR | |
| Hydrochloric Acid SCHEMBL29134312 | 0.95 | — | — | |
| SCHEMBL24197132 | 0.79 | HTR6 (0.31) | — | |
| SCHEMBL26803559 | 0.78 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL27097467 | 0.76 | SLC6A2 (0.37) | TSHRHRH3MEN1KMT2A | |
| SCHEMBL23439643 | 0.75 | LMNA (0.33) | HRH3 | |
| SCHEMBL31637071 | 0.73 | TSHR (0.40) | TSHRHRH3MEN1KMT2A | |
| SCHEMBL25338400 | 0.72 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL23163792 | 0.70 | TSHR (0.37) | TSHRMEN1KMT2A | |
| SCHEMBL25466870 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099344-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4 | ARVINAS OPERATIONS, INC. | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099344-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4 | IRAK1, IRAK4, IRAK2 | TSHR 3539/4885HRH3 3196/4885MEN1 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.