Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23442001 | 0.90 | EGFR (0.69) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL23441888 | 0.90 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL22595132 | 0.90 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL23441900 | 0.89 | EGFR (0.59) | EGFRBTKINSRALK | |
| Hydrochloric Acid SCHEMBL29094608 | 0.88 | EGFR (0.50) | EGFRBTKALK | |
| SCHEMBL29084096 | 0.88 | EGFR (0.71) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL23442858 | 0.88 | EGFR (0.66) | EGFRBTKINSRIGF1RALK | |
| Hydrochloric Acid SCHEMBL31155437 | 0.88 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL22595520 | 0.85 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL22595192 | 0.84 | EGFR (0.54) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104441-A1 | POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR | 江苏先声药业有限公司 | 2021-06-03 | — | — | WO | disclosed |