SCHEMBL23442477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24442807	0.89	RARB (0.43)	NPSR1MAPTSMN1; SMN2AKR1C3AKR1C2
	SCHEMBL23442800	0.85	RARB (0.46)	RXRARARBRARGMEN1KMT2A
	SCHEMBL29945232	0.85	RARB (0.46)	RXRARARBRARGMEN1KMT2A
	SCHEMBL24772162	0.82	NPSR1 (0.46)	NPSR1MAPTSMN1; SMN2GRM5AKR1C3
	SCHEMBL23446728	0.78	RARB (0.39)	TP53RXRARARBRARGRXRB
	SCHEMBL23118193	0.78	ABCG2 (0.39)	NPSR1MAPTABCG2AKR1C3AKR1C2
	SCHEMBL24174910	0.77	NPSR1 (0.59)	NPSR1L3MBTL1FLT1FLT4KDR
	SCHEMBL9188311	0.76	NPSR1 (0.62)	NPSR1L3MBTL1FLT1FLT4KDR
	SCHEMBL24442968	0.76	RARB (0.39)	RXRARARBRARGRXRBRXRG
	SCHEMBL27395131	0.75	RARB (0.51)	AKR1C3RXRARARBRARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.