Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.75 |
| ▸ | RORC | P51449 | 15/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anatibant SCHEMBL1649974 | 0.86 | BDKRB2 (1.00) | BDKRB2RORC | |
| Anatibant SCHEMBL29379305 | 0.86 | BDKRB2 (1.00) | BDKRB2RORC | |
| Anatibant SCHEMBL6945415 | 0.86 | BDKRB2 (1.00) | BDKRB2RORC | |
| Anatibant SCHEMBL29403189 | 0.86 | BDKRB2 (1.00) | BDKRB2RORC | |
| Anatibant SCHEMBL8045259 | 0.85 | BDKRB2 (0.99) | BDKRB2RORC | |
| Anatibant SCHEMBL8045426 | 0.85 | BDKRB2 (0.98) | BDKRB2RORC | |
| Anatibant SCHEMBL29711321 | 0.85 | BDKRB2 (0.98) | BDKRB2RORC | |
| SCHEMBL6948870 | 0.85 | BDKRB2 (0.98) | BDKRB2RORC | |
| SCHEMBL6950081 | 0.84 | BDKRB2 (0.96) | BDKRB2RORC | |
| SCHEMBL1560922 | 0.84 | BDKRB2 (0.55) | BDKRB2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1901775-B1 | KININ ANTAGONISTS FOR TREATING BLADDER DYSFUNCTION | JERINI AG (DE) | 2011-08-24 | — | — | EP | claimed |
| EP-1901775-B1 | KININ ANTAGONISTS FOR TREATING BLADDER DYSFUNCTION | JERINI AG (DE) | 2011-08-24 | — | — | EP | disclosed |