SCHEMBL2344376

SCHEMBL2344376

Nc1c(Cl)c(C(=O)O)nc(Cl)c1Br

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.69
LMNA P02545 3/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 2/20 0.36
ATM Q13315 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NOX1 Q9Y5S8 1/20 0.33
KMO O15229 1/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
GLA P06280 3/20 0.33
HPGD P15428 3/20 0.33
HSD17B10 Q99714 3/20 0.33
PLAU P00749 2/20 0.33
CYP1A2 P05177 2/20 0.33
SLC9A1 P19634 2/20 0.33
SLC22A1 O15245 1/20 0.33
HTR1A P08908 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Picloram SCHEMBL29388079 0.82 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL8467014 0.82 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL13299 0.82 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL29705200 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL28547325 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL7112378 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL15437675 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL724603 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL5086801 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL18112562 0.80 TDP1 (0.96) TDP1LMNAGAAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498413-B1 4-Aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2011-08-31 EP disclosed
EP-1246802-B1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-03-14 EP disclosed
EP-1498413-A1 4-Aminopicolinates and their use as herbicides Dow AgroSciences LLC (US) 2005-01-19 EP disclosed
EP-1246802-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2002-10-09 EP disclosed
US-20010047099-A1 4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC 2001-11-29 US disclosed
US-6297197-B1 DEMONSTRATING A BROAD SPECTRUM OF WEED CONTROL. DOW AGROSCIENCES LLC 2001-10-02 US disclosed
WO-2001051468-A1 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047099-A1 4-aminopicolinates and their use as herbicides AADAT, ABAT, DDT TDP1 3400/4885LMNA 4475/4885GAA 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.