Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342066 | 0.91 | MAOB (0.39) | MRGPRX4LRRK2MAOB | |
| SCHEMBL6330377 | 0.64 | TDP1 (0.63) | KMT2AMAPTTDP1VNN1 | |
| SCHEMBL18668838 | 0.63 | TDP1 (0.53) | KMT2ATDP1 | |
| SCHEMBL4030533 | 0.62 | GSK3B (0.54) | MRGPRX4NR4A2MAPTVNN1 | |
| SCHEMBL29441888 | 0.61 | GSK3B (0.62) | MRGPRX4 | |
| SCHEMBL60691 | 0.61 | GSK3B (0.62) | MRGPRX4 | |
| SCHEMBL7566253 | 0.61 | FFAR1 (0.46) | MRGPRX4KMT2AMAOBCTSLCTSS | |
| SCHEMBL29248543 | 0.61 | FFAR1 (0.50) | MRGPRX4PPARAMAOB | |
| Hydrochloric Acid SCHEMBL2031438 | 0.60 | GSK3B (0.61) | MRGPRX4 | |
| SCHEMBL11706688 | 0.60 | GSK3B (0.61) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360150-A1 | Method for the separation of intermediates which may be used for the preparation of escitalopram | H. Lundbeck A/S (DK) | 2011-08-24 | — | — | EP | disclosed |
| US-20070129561-A1 | Method for the separation of intermediates which may be used for the preparation of escitalopram | H. LUNDBECK A/S (DK) | 2007-06-07 | — | — | US | disclosed |
| EP-1534654-A1 | METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004014821-A1 | METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129561-A1 | Method for the separation of intermediates which may be used for the preparation of escitalopram | MAOB, HSD17B14, MAOA | PTGER1 1505/4885MRGPRX4 4634/4885PPARA 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.