SCHEMBL7566253

SCHEMBL7566253

N#Cc1cccc(C(N)C(=O)OCc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 1/20 0.46
GRM4 Q14833 1/20 0.46
LMNA P02545 1/20 0.44
TNF P01375 1/20 0.44
GPR34 Q9UPC5 1/20 0.43
CTSL P07711 1/20 0.43
CTSS P25774 1/20 0.43
TACR1 P25103 1/20 0.42
MRGPRX1 Q96LB2 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CNR1 P21554 1/20 0.42
MAOB P27338 1/20 0.42
LTA4H P09960 1/20 0.41
LAP3 P28838 1/20 0.41
MRGPRX4 Q96LA9 2/20 0.41
PPIA P62937 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1624864 0.83 FFAR1 (0.53) FFAR1FFAR4GRM4LMNAGPR34
SCHEMBL18946054 0.82 PDCD1 (0.49) FFAR1GRM4TNF
SCHEMBL29248543 0.82 FFAR1 (0.50) FFAR1FFAR4LMNATACR1MRGPRX1
SCHEMBL1745793 0.81 ALDH1A1 (0.53) LMNATACR1KMT2ASMN1; SMN2LTA4H
SCHEMBL8804399 0.81 ALDH1A1 (0.53) LMNATACR1KMT2ASMN1; SMN2LTA4H
SCHEMBL11472824 0.81 ALDH1A1 (0.53) LMNATACR1KMT2ASMN1; SMN2LTA4H
Hydrochloric Acid SCHEMBL31652401 0.81 KYNU (0.48) LMNAKMT2ASMN1; SMN2LTA4HLAP3
Hydrochloric Acid SCHEMBL10886394 0.80 ALDH1A1 (0.52) LMNATACR1KMT2ASMN1; SMN2LTA4H
SCHEMBL5549275 0.79 FOLH1 (0.46) FFAR1FFAR4LMNAGPR34TACR1
SCHEMBL18116486 0.78 GRM4 (0.54) GRM4TNFKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151534-A1 Antithrombotic compounds SERPINC1, PF4, F2 FFAR1 1827/4885FFAR4 1821/4885GRM4 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.