SCHEMBL2344657

SCHEMBL2344657

CCO[Sn](O[Sn](OCC)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 1/20 0.34
LTA4H P09960 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
KCNH2 Q12809 1/20 0.34
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.32
ACHE P22303 1/20 0.32
NR1I2 O75469 1/20 0.32
RELA Q04206 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2331293 0.91 NPSR1 (0.38) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2347611 0.83 MEN1 (0.41) ALDH1A1LTA4HTP53MEN1KMT2A
SCHEMBL2325371 0.79 LTA4H (0.44) NPSR1ALDH1A1LTA4HL3MBTL1MEN1
SCHEMBL2325321 0.78 LTA4H (0.44) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2473222 0.78 TRPA1 (0.33) ALDH1A1L3MBTL1
SCHEMBL2347755 0.77 LTA4H (0.43) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2344253 0.77 LTA4H (0.43) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2348524 0.77 LTA4H (0.43) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2325240 0.77 LTA4H (0.43) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2
SCHEMBL2339079 0.77 LTA4H (0.43) NPSR1ALDH1A1LTA4HL3MBTL1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535896-B1 PROCESS FOR PRODUCING CARBONIC ESTER ASAHI KASEI CHEMICALS CORP (JP) 2015-10-07 EP disclosed
EP-1460056-B1 METHOD FOR PRODUCING A CARBONIC ESTER ASAHI KASEI CHEMICALS CORP (JP) 2011-10-05 EP disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-7446218-B2 Process for producing carbonic ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-11-04 US disclosed
US-7435842-B2 Process for producing carbonic ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-10-14 US disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed
US-20050240045-A1 Process for producing carbonic ester ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-10-27 US disclosed
EP-1535896-A1 PROCESS FOR PRODUCING CARBONIC ESTER Asahi Kasei Chemicals Corporation (JP) 2005-06-01 EP disclosed
US-20050080274-A1 Process for producing carbonic ester ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-04-14 US disclosed
EP-1460056-A1 PROCESS FOR PRODUCING CARBONIC ESTER Asahi Kasei Chemicals Corporation (JP) 2004-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080274-A1 Process for producing carbonic ester CYP2E1, ADH1A, ALKBH3 NPSR1 4658/4885ALDH1A1 264/4885LTA4H 1561/4885
US-20050240045-A1 Process for producing carbonic ester ALKBH3, CYP4A11, CYP2E1 NPSR1 4316/4885ALDH1A1 471/4885LTA4H 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.