Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
| ▸ | CTSK | P43235 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23085809 | 0.92 | CTSS (0.57) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL23448102 | 0.87 | CTSS (0.50) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL3821800 | 0.86 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL27487987 | 0.86 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL16163459 | 0.86 | CTSS (0.63) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL7235877 | 0.86 | CTSS (0.63) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL1486267 | 0.86 | CTSS (0.63) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL27487988 | 0.86 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL7673164 | 0.85 | CTSS (0.51) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL6572493 | 0.84 | PPARA (0.54) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106000-A1 | PROCESS FOR MAKING BIARYL-BRIDGED CYCLIC PEPTIDES | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2021-06-03 | — | — | WO | disclosed |