SCHEMBL23085809

SCHEMBL23085809

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSS P25774 8/20 0.57
CTSK P43235 7/20 0.57
CTSB P07858 4/20 0.53
CTSL P07711 2/20 0.53
REN P00797 1/20 0.51
ACE P12821 1/20 0.49
KLK5 Q9Y337 1/20 0.48
PTPN1 P18031 1/20 0.48
BCL2 P10415 1/20 0.48
TACR1 P25103 1/20 0.48
AKT1 P31749 1/20 0.48
TYR P14679 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9888267 0.93 PPARA (0.54) CTSSCTSKCTSBCTSLACE
SCHEMBL6572493 0.93 PPARA (0.54) CTSSCTSKCTSBCTSLACE
SCHEMBL23447154 0.92 CTSS (0.54) CTSSCTSKCTSBCTSLREN
SCHEMBL27487988 0.89 CTSS (0.65) CTSSCTSKCTSBCTSLREN
SCHEMBL16163459 0.89 CTSS (0.63) CTSSCTSKCTSBCTSLACE
SCHEMBL3821800 0.89 CTSS (0.65) CTSSCTSKCTSBCTSLREN
SCHEMBL27487987 0.89 CTSS (0.65) CTSSCTSKCTSBCTSLREN
SCHEMBL7235877 0.89 CTSS (0.63) CTSSCTSKCTSBCTSLACE
SCHEMBL1486267 0.89 CTSS (0.63) CTSSCTSKCTSBCTSLACE
SCHEMBL23069526 0.88 CTSS (0.63) CTSSCTSKCTSBCTSLREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220362386-A1 LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF NEURODERM LTD (IL) 2022-11-17 US disclosed
EP-4025200-A1 LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF Neuroderm Ltd (IL) 2022-07-13 EP disclosed
WO-2021044420-A1 LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF NEURODERM, LTD. (IL) 2021-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220362386-A1 LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF DAO, DDC, AADAT CTSS 1408/4885CTSK 1616/4885CTSB 1002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.