SCHEMBL2344866

SCHEMBL2344866

CCCS(=O)(=O)ONCCCCCCCCCCCCCCCC(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
GRIA1 P42261 3/20 0.32
PPARA Q07869 2/20 0.31
FUT7 Q11130 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17508561 1.00 TP53 (0.33) TP53GRIA1PPARAFUT7EPHX1
SCHEMBL28315394 0.84 PPARA (0.44) PPARAEPHX1
SCHEMBL2597785 0.84 PPARA (0.44) PPARAEPHX1
SCHEMBL28350946 0.84 PPARA (0.44) PPARAEPHX1
SCHEMBL27761167 0.84 PPARA (0.44) PPARAEPHX1
SCHEMBL28611800 0.84 PPARA (0.44) PPARAEPHX1
SCHEMBL31348971 0.77 PPARA (0.44) PPARAEPHX1
SCHEMBL31348943 0.77 PPARA (0.44) PPARAEPHX1
SCHEMBL31348932 0.77 PPARA (0.44) PPARAEPHX1
SCHEMBL28325394 0.76 CA1 (0.39) PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007622-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE UNIV FLORIDA STATE RES FOUND (US) 2026-01-08 US claimed
US-20250041253-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2025-02-06 US claimed
US-12161611-B2 Niclosamide formulations and methods of use FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2024-12-10 US claimed
US-20230390225-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-12-07 US claimed
US-11771668-B2 Niclosamide formulations and methods of use FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-10-03 US claimed
EP-3320921-B1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA INC (US) 2022-01-05 EP claimed
US-20210308079-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-10-07 US claimed
US-20180153817-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA, INC. (US) 2018-06-07 US claimed
EP-3320921-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS Ala Wai Pharma, Inc. (US) 2018-05-16 EP claimed
US-20170157059-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA, INC. (US) 2017-06-08 US claimed
US-9579383-B2 Formulations for enhanced bioavailability of orally administered polar agents ALA WAI PHARMA, INC. (US) 2017-02-28 US claimed
US-20140072627-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA, INC. (US) 2014-03-13 US claimed
US-8609139-B2 Formulations for enhanced bioavailability of orally administered polar agents ALA WAI PHARMA, INC. (US) 2013-12-17 US claimed
US-20110206764-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS UNIVERSITY OF HAWAII 2011-08-25 US claimed
EP-2217216-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS Scolr Pharma, Inc. (US) 2010-08-18 EP claimed
WO-2009061805-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SCOLR PHARMA, INC. (US) 2009-05-14 WO claimed
US-12533416-B2 Krill oil for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents ID CARE UG (haftungsbeschränkt) (DE) 2026-01-27 US disclosed
US-20260007622-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE UNIV FLORIDA STATE RES FOUND (US) 2026-01-08 US disclosed
EP-2217216-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS Scolr Pharma, Inc. (US) 2010-08-18 EP disclosed
WO-2009061805-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SCOLR PHARMA, INC. (US) 2009-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041253-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE TMPRSS2, NCSTN, PRSS2 TP53 1645/4885GRIA1 2311/4885PPARA 1104/4885
US-20230390225-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE TMPRSS2, NCSTN, PRSS2 TP53 1645/4885GRIA1 2311/4885PPARA 1104/4885
US-20260007622-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE TMPRSS2, PKD2, DSP TP53 1454/4885GRIA1 3689/4885PPARA 1821/4885
US-20210308079-A1 NICLOSAMIDE FORMULATIONS AND METHODS OF USE TMPRSS2, NCSTN, PRSS2 TP53 1645/4885GRIA1 2311/4885PPARA 1104/4885
US-20170157059-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 TP53 2031/4885GRIA1 4244/4885PPARA 794/4885
US-11771668-B2 Niclosamide formulations and methods of use TMPRSS2, NCSTN, PRSS2 TP53 1645/4885GRIA1 2311/4885PPARA 1104/4885
US-20110206764-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 TP53 2031/4885GRIA1 4244/4885PPARA 794/4885
US-12161611-B2 Niclosamide formulations and methods of use TMPRSS2, NCSTN, PRSS2 TP53 1645/4885GRIA1 2311/4885PPARA 1104/4885
US-20180153817-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 TP53 2031/4885GRIA1 4244/4885PPARA 794/4885
US-12533416-B2 Krill oil for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents CYP8B1, CEL, KLK8 TP53 1590/4885GRIA1 4743/4885PPARA 749/4885
US-20140072627-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 TP53 2031/4885GRIA1 4244/4885PPARA 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.