Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MERTK | Q12866 | 4/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644500 | 0.82 | CHRM3 (0.44) | MAPK8MERTKNR2F2NPSR1MEN1 | |
| SCHEMBL496548 | 0.79 | MAPK8 (0.43) | MAPK8MERTKALDH1A1KMT2ACTSL | |
| SCHEMBL495797 | 0.79 | KMT2A (0.43) | MAPK8MERTKMEN1ALDH1A1KMT2A | |
| SCHEMBL496141 | 0.78 | POLB (0.54) | MAPK8MERTKAXLNPSR1RAB9A | |
| SCHEMBL1179794 | 0.75 | GABRP (0.46) | NPSR1MEN1NPC1ALDH1A1LMNA | |
| SCHEMBL4402475 | 0.74 | SYK (0.45) | MAPK8MERTKKMT2AHCAR3SYK | |
| SCHEMBL20299364 | 0.72 | KMT2A (0.61) | MAPK8MERTKFLT3TYRO3GAS6 | |
| SCHEMBL16878622 | 0.71 | HCAR3 (0.41) | RAB9AHCAR3SYK | |
| SCHEMBL13518145 | 0.70 | KMT2A (0.58) | MAPK8MERTKFLT3TYRO3GAS6 | |
| SCHEMBL2344869 | 0.70 | ADORA3 (0.43) | MAPK8NPC1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |