Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23449223 | 0.89 | S1PR1 (0.43) | S1PR1S1PR4S1PR3S1PR5PLAU | |
| SCHEMBL23448620 | 0.73 | CA1 (0.45) | PLAUHPNHSD17B10MAPTMEN1 | |
| SCHEMBL23976663 | 0.73 | MEN1 (0.48) | TSHRHSD17B10CAPN1EHMT2MAPT | |
| SCHEMBL23449167 | 0.72 | NPSR1 (0.40) | TSHRHSD17B10CAPN1CTSBEHMT2 | |
| SCHEMBL26249741 | 0.72 | S1PR1 (0.45) | S1PR1S1PR4S1PR3S1PR5SIRT2 | |
| SCHEMBL23448716 | 0.72 | KDM1A (0.41) | KDM1ARCOR1EHMT2MAPTMEN1 | |
| SCHEMBL23448721 | 0.72 | HSD17B10 (0.58) | PLAUHPNHSD17B10EHMT2MAPT | |
| SCHEMBL26253054 | 0.71 | S1PR1 (0.47) | S1PR1S1PR4S1PR3S1PR5SIRT2 | |
| SCHEMBL23448718 | 0.70 | L3MBTL1 (0.41) | TSHREHMT2MAPTMEN1ALDH1A1 | |
| SCHEMBL9381846 | 0.70 | KDM1A (0.52) | KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106988-A1 | G9a INHIBITOR | 杏林製薬株式会社 | 2021-06-03 | — | — | WO | disclosed |