Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23449238 | 0.91 | NPSR1 (0.36) | NPSR1CTSKEHMT2CAPN1CTSB | |
| SCHEMBL26087650 | 0.73 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL23448822 | 0.72 | KDM1A (0.43) | EHMT2CAPN1CTSBTSHRHSD17B10 | |
| SCHEMBL23449212 | 0.72 | SPHK1 (0.46) | CTSKEHMT2TLR2CTSLCTSS | |
| SCHEMBL20806152 | 0.70 | DPP7 (0.42) | CTSKCTSSTSHR | |
| SCHEMBL23449236 | 0.69 | SPHK1 (0.55) | TLR2 | |
| SCHEMBL23977990 | 0.68 | LMNA (0.47) | CTSKCYP2C9 | |
| SCHEMBL12452819 | 0.65 | NPSR1 (0.65) | NPSR1TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13350786 | 0.65 | SLC15A1 (0.43) | CTSKTSHR | |
| SCHEMBL23449223 | 0.65 | S1PR1 (0.43) | TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106988-A1 | G9a INHIBITOR | 杏林製薬株式会社 | 2021-06-03 | — | — | WO | disclosed |