Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP10 | P09238 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP12 | P39900 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26253054 | 0.99 | S1PR1 (0.47) | S1PR1S1PR4S1PR3S1PR5MMP2 | |
| SCHEMBL26248616 | 0.83 | ADRB2 (0.39) | MMP8ITGB3ITGA2BHDAC6SMN1; SMN2 | |
| SCHEMBL22527182 | 0.82 | SPHK1 (0.32) | S1PR1S1PR4S1PR3S1PR5MMP2 | |
| SCHEMBL22527166 | 0.82 | MEN1 (0.33) | S1PR1S1PR4S1PR3S1PR5KMT2A | |
| SCHEMBL22526934 | 0.81 | S1PR1 (0.62) | S1PR1S1PR4S1PR3S1PR5AURKA | |
| SCHEMBL22525595 | 0.78 | S1PR1 (0.58) | S1PR1S1PR4S1PR3S1PR5AURKA | |
| SCHEMBL22526152 | 0.76 | SIRT5 (0.54) | MMP2MMP10MMP9MMP8MMP12 | |
| SCHEMBL26249029 | 0.76 | MPO (0.34) | MMP2MMP9KMT2AMEN1LMNA | |
| SCHEMBL25382557 | 0.75 | HDAC4 (0.55) | S1PR1S1PR4S1PR3S1PR5MMP2 | |
| SCHEMBL22526688 | 0.75 | HDAC4 (0.55) | S1PR1S1PR4S1PR3S1PR5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | S1PR1 3138/4885S1PR4 2517/4885S1PR3 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.