SCHEMBL23450915

SCHEMBL23450915

CC(C)(C)c1ccc(Nc2ccc3c(c2)-c2ccccc2C3(C)C)c(-c2ccc3c(c2)C(C)(C)CCC3(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 7/20 0.40
▸ RARG P13631 6/20 0.40
▸ RXRA P19793 3/20 0.40
▸ JAK2 O60674 1/20 0.34
▸ JAK3 P52333 1/20 0.34
▸ KCNK18 Q7Z418 1/20 0.33
▸ RARA P10276 7/20 0.32
▸ RXRB P28702 1/20 0.32
▸ CYP26A1 O43174 4/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ PGR P06401 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ ADORA3 P0DMS8 1/20 0.31
▸ TBXA2R P21731 1/20 0.31
▸ BLVRB P30043 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ P2RY1 P47900 1/20 0.31
▸ CYP26B1 Q9NR63 3/20 0.31
▸ PDK2 Q15119 1/20 0.31
▸ NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23927546 0.88 RARA (0.39) RARBRARGRXRAJAK2JAK3
SCHEMBL30363478 0.86 KCNK18 (0.37) KCNK18P2RY1PDK2NPC1ALDH1A1
SCHEMBL22934074 0.84 CYP26A1 (0.40) RARBRARGRXRAJAK2JAK3
SCHEMBL23444328 0.84 RARA (0.39) RARBRARGRXRAJAK2JAK3
SCHEMBL25810318 0.82 JAK2 (0.34) RARBRARGRXRAJAK2JAK3
SCHEMBL30363263 0.79 PDK2 (0.39) KCNK18PDK2NPC1ALDH1A1PLA2G1B
SCHEMBL26599461 0.79 PDK2 (0.39) KCNK18PDK2NPC1ALDH1A1PLA2G1B
SCHEMBL24772229 0.79 KCNK18 (0.36) KCNK18P2RY1PDK2NPC1ALDH1A1
SCHEMBL24772649 0.79 CYP26A1 (0.36) RARBRARGRXRAJAK2JAK3
SCHEMBL26951736 0.79 RARB (0.46) RARBRARGRXRAJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220263027-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2022-08-18 — — US disclosed
CN-113795497-A Compound and organic light emitting device including the same 株式会社LG化学 2021-12-14 — — CN disclosed
WO-2021107359-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-06-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220263027-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CYP1A1, AOX1, ARNT RARB 1934/4885RARG 1708/4885RXRA 638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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