Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23451136 | 0.90 | TSHR (0.47) | TSHRLPAR1LPAR2ENPP2PLA2G2A | |
| SCHEMBL23451114 | 0.90 | PLA2G2A (0.39) | TSHRLPAR1LPAR2ENPP2PLA2G2A | |
| SCHEMBL23451011 | 0.88 | GLP1R (0.51) | LPAR1PLA2G2AGLP1R | |
| SCHEMBL18905064 | 0.87 | ADRA1A (0.46) | TSHRLPAR1LPAR2ENPP2ADRA1A | |
| SCHEMBL14265137 | 0.87 | PLA2G2A (0.44) | TSHRPLA2G2AKDM4EMAPK1HIF1A | |
| SCHEMBL23442008 | 0.87 | PLA2G2A (0.44) | TSHRPLA2G2AKDM4EMAPK1HIF1A | |
| SCHEMBL23451009 | 0.86 | PLA2G2A (0.43) | TSHRPLA2G2AADRA1AKDM4EMAPK1 | |
| SCHEMBL23452878 | 0.84 | KDM4E (0.44) | TSHRLPAR1LPAR2ENPP2PLA2G2A | |
| SCHEMBL23451013 | 0.84 | PLA2G2A (0.39) | TSHRPLA2G2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14450493 | 0.82 | LPAR1 (0.43) | TSHRLPAR1LPAR2ENPP2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108662-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | DTX PHARMA, INC. (US) | 2021-06-03 | — | — | WO | disclosed |