Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14265137 | 1.00 | PLA2G2A (0.44) | PLA2G2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23451013 | 0.91 | PLA2G2A (0.39) | PLA2G2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23451114 | 0.91 | PLA2G2A (0.39) | PLA2G2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL13208810 | 0.90 | MTNR1A (0.42) | PLA2G2AMTNR1AMTNR1BSMN1; SMN2MAPK1 | |
| SCHEMBL23451007 | 0.87 | TSHR (0.43) | PLA2G2ASMN1; SMN2MAPK1KDM4EHIF1A | |
| SCHEMBL14225754 | 0.84 | MEN1 (0.43) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL14225755 | 0.84 | MEN1 (0.43) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL14225742 | 0.84 | MEN1 (0.43) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL25517754 | 0.83 | KDM4E (0.47) | PLA2G2AMTNR1AMTNR1BMAPK1KDM4E | |
| SCHEMBL23451916 | 0.83 | PLA2G2A (0.43) | PLA2G2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091985-A1 | COMPOUNDS TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE | DTX PHARMA, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023086978-A2 | BRANCHED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086979-A1 | STAGGERED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2021108662-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | DTX PHARMA, INC. (US) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021108640-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | DTX PHARMA, INC. (US) | 2021-06-03 | — | — | WO | disclosed |