Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24097054 | 0.79 | ATM (0.44) | ATMLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL18868913 | 0.69 | CES2 (0.37) | ATMLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL15216219 | 0.68 | ATM (0.35) | ATMLMNAL3MBTL1HSD17B10SMN1; SMN2 | |
| SCHEMBL20999159 | 0.68 | AKT1 (0.36) | ATMLMNAL3MBTL1HSD17B10SMN1; SMN2 | |
| SCHEMBL2490467 | 0.68 | KDM1A (0.42) | ATMMTNR1AMTNR1BCYP1A2CYP2D6 | |
| SCHEMBL1193963 | 0.68 | KDM1A (0.42) | ATMMTNR1AMTNR1BCYP1A2CYP2D6 | |
| SCHEMBL5028746 | 0.68 | KDM1A (0.42) | ATMMTNR1AMTNR1BCYP1A2CYP2D6 | |
| SCHEMBL20077791 | 0.67 | DEGS1 (0.41) | ATMLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL18929539 | 0.67 | ATM (0.34) | ATMSMN1; SMN2POLB | |
| SCHEMBL20470769 | 0.66 | AKT1 (0.46) | ATMLMNAMAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |